Upregulation of brain hepcidin in prion diseases: Short title: Hepcidin and brain iron accumulation

Accumulation of redox-active iron in human sporadic Creutzfeldt-Jakob disease (sCJD) brain tissue and scrapie-infected mouse brains has been demonstrated previously. Here, we explored whether upregulation of local hepcidin secreted within the brain is the underlying cause of iron accumulation and as...

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Detalhes bibliográficos
Publicado no:Prion
Main Authors: Chaudhary, Suman, Ashok, Ajay, Wise, Aaron S., Rana, Neil A., McDonald, Dallas, Kritikos, Alexander E., Kong, Qingzhong, Singh, Neena
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2021
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8259718/
https://ncbi.nlm.nih.gov/pubmed/34224321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19336896.2021.1946377
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