IgM Autoantibodies to Complement Factor H in Atypical Hemolytic Uremic Syndrome

BACKGROUND: Atypical hemolytic uremic syndrome (aHUS), a severe thrombotic microangiopathy, is often related to complement dysregulation, but the pathomechanisms remain unknown in at least 30% of patients. Researchers have described autoantibodies to complement factor H of the IgG class in 10% of pa...

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Dettagli Bibliografici
Pubblicato in:J Am Soc Nephrol
Autori principali: Cugno, Massimo, Berra, Silvia, Depetri, Federica, Tedeschi, Silvana, Griffini, Samantha, Grovetti, Elena, Caccia, Sonia, Cresseri, Donata, Messa, Piergiorgio, Testa, Sara, Giglio, Fabio, Peyvandi, Flora, Ardissino, Gianluigi
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Nephrology 2021
Soggetti:
Clinical Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8259677/
https://ncbi.nlm.nih.gov/pubmed/33712527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2020081224
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