The host transcriptional response to Candidemia is dominated by neutrophil activation and heme biosynthesis and supports novel diagnostic approaches

BACKGROUND: Candidemia is one of the most common nosocomial bloodstream infections in the United States, causing significant morbidity and mortality in hospitalized patients, but the breadth of the host response to Candida infections in human patients remains poorly defined. METHODS: In order to bet...

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Veröffentlicht in:Genome Med
Hauptverfasser: Steinbrink, Julie M., Myers, Rachel A., Hua, Kaiyuan, Johnson, Melissa D., Seidelman, Jessica L., Tsalik, Ephraim L., Henao, Ricardo, Ginsburg, Geoffrey S., Woods, Christopher W., Alexander, Barbara D., McClain, Micah T.
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2021
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8259367/
https://ncbi.nlm.nih.gov/pubmed/34225776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13073-021-00924-9
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