Infliximab clearance decreases in the second and third trimesters of pregnancy in inflammatory bowel disease

BACKGROUND: Infliximab therapy during pregnancy in inflammatory bowel disease is challenged by a dilemma between maintaining adequate maternal disease control while minimizing fetal infliximab exposure. We investigated the effects of pregnancy on infliximab pharmacokinetics. METHODS: The study popul...

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Bibliografiske detaljer
Udgivet i:United European Gastroenterol J
Main Authors: Grišić, Ana‐Marija, Dorn‐Rasmussen, Maria, Ungar, Bella, Brynskov, Jørn, Ilvemark, Johan F. K. F., Bolstad, Nils, Warren, David J., Ainsworth, Mark A., Huisinga, Wilhelm, Ben‐Horin, Shomron, Kloft, Charlotte, Steenholdt, Casper
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2021
Fag:
Inflammatory Bowel Disease
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8259366/
https://ncbi.nlm.nih.gov/pubmed/33079627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2050640620964619
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