Lack of Mucosal Cholinergic Innervation Is Associated With Increased Risk of Enterocolitis in Hirschsprung’s Disease

BACKGROUND & AIMS: Hirschsprung’s disease (HSCR) is a congenital intestinal motility disorder defined by the absence of enteric neuronal cells (ganglia) in the distal gut. The development of HSCR-associated enterocolitis remains a life-threatening complication. Absence of enteric ganglia implica...

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Udgivet i:Cell Mol Gastroenterol Hepatol
Main Authors: Keck, Simone, Galati-Fournier, Virginie, Kym, Urs, Moesch, Michèle, Usemann, Jakob, Müller, Isabelle, Subotic, Ulrike, Tharakan, Sasha J., Krebs, Thomas, Stathopoulos, Eleuthere, Schmittenbecher, Peter, Cholewa, Dietmar, Romero, Philipp, Reingruber, Bertram, Bruder, Elisabeth, Group, NIG Study, Holland-Cunz, Stefan
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2021
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8258990/
https://ncbi.nlm.nih.gov/pubmed/33741501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jcmgh.2021.03.004
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