Intraoperative opioid exposure, tumour genomic alterations, and survival differences in people with lung adenocarcinoma

BACKGROUND: Opioids have been linked to worse oncologic outcomes in surgical patients. Studies in certain cancer types have identified associations between survival and intra-tumoural opioid receptor gene alterations, but no study has investigated whether the tumour genome interacts with opioid expo...

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Bibliographische Detailangaben
Veröffentlicht in:Br J Anaesth
Hauptverfasser: Connolly, James G., Tan, Kay See, Mastrogiacomo, Brooke, Dycoco, Joseph, Caso, Raul, Jones, Gregory D., McCormick, Patrick J., Sanchez-Vega, Francisco, Irie, Takeshi, Scarpa, Joseph R., Gupta, Hersh V., Adusumilli, Prasad S., Rocco, Gaetano, Isbell, James M., Bott, Matthew J., Fischer, Gregory W., Jones, David R., Mincer, Joshua S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2021
Schlagworte:
Clinical Investigation
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8258974/
https://ncbi.nlm.nih.gov/pubmed/34147159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bja.2021.03.030
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