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Bosutinib reduces endothelial permeability and organ failure in a rat polytrauma transfusion model()
BACKGROUND: Trauma-induced shock is associated with endothelial dysfunction. We examined whether the tyrosine kinase inhibitor bosutinib as an adjunct therapy to a balanced blood component resuscitation strategy reduces trauma-induced endothelial permeability, thereby improving shock reversal and li...
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| Izdano u: | Br J Anaesth |
|---|---|
| Glavni autori: | , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Elsevier
2021
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8258973/ https://ncbi.nlm.nih.gov/pubmed/33685634 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bja.2021.01.032 |
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