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The LIFT trial: study protocol for a double-blind, randomised, placebo-controlled trial of K(+)-binder Lokelma for maximisation of RAAS inhibition in CKD patients with heart failure

BACKGROUND: CKD is common in heart failure (HF) and associated with morbidity and mortality, yet life-prolonging medications such as renin-angiotensin-aldosterone inhibitors (RAASi) are underused due to risk of hyperkalaemia. Sodium zirconium cyclosilicate (SZC) is a potassium-binding medication tha...

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Bibliografiske detaljer
Udgivet i:BMC Nephrol
Main Authors: Murphy, Daniel, Ster, Irina Chis, Kaski, Juan-Carlos, Anderson, Lisa, Banerjee, Debasish
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8258742/
https://ncbi.nlm.nih.gov/pubmed/34229607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12882-021-02439-2
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