Acute Kidney Injury is Aggravated in Aged Mice by the Exacerbation of Proinflammatory Processes

Acute kidney injury (AKI) is more frequent in elderly patients. Mechanisms contributing to AKI (tubular cell death, inflammatory cell infiltration, impaired mitochondrial function, and prolonged cell-cycle arrest) have been linked to cellular senescence, a process implicated in regeneration failure...

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Vydáno v:Front Pharmacol
Hlavní autoři: Marquez-Exposito, Laura, Tejedor-Santamaria, Lucia, Santos-Sanchez, Laura, Valentijn, Floris A., Cantero-Navarro, Elena, Rayego-Mateos, Sandra, Rodrigues-Diez, Raul R., Tejera-Muñoz, Antonio, Marchant, Vanessa, Sanz, Ana B., Ortiz, Alberto, Goldschmeding, Roel, Ruiz-Ortega, Marta
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2021
Témata:
Pharmacology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8258347/
https://ncbi.nlm.nih.gov/pubmed/34239439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2021.662020
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