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Targeting epigenetic regulatory machinery to overcome cancer therapy resistance

Drug resistance, either intrinsic or acquired, represents a major hurdle to achieving optimal therapeutic outcomes during cancer treatment. In addition to acquisition of resistance-conferring genetic mutations, accumulating evidence suggests an intimate involvement of the epigenetic machinery in thi...

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Bibliographic Details
Published in:Semin Cancer Biol
Main Authors: Guo, Lei, Lee, Yi-Tsang, Zhou, Yubin, Huang, Yun
Format: Artigo
Language:Inglês
Published: 2022
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8257754/
https://ncbi.nlm.nih.gov/pubmed/33421619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semcancer.2020.12.022
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