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Post-capillary venules are the key locus for transcytosis-mediated brain delivery of therapeutic nanoparticles
Effective treatments of neurodegenerative diseases require drugs to be actively transported across the blood-brain barrier (BBB). However, nanoparticle drug carriers explored for this purpose show negligible brain uptake, and the lack of basic understanding of nanoparticle-BBB interactions underlies...
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| Publicado no: | Nat Commun |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8257611/ https://ncbi.nlm.nih.gov/pubmed/34226541 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-24323-1 |
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