hsa-miR-199b-3p Prevents the Epithelial-Mesenchymal Transition and Dysfunction of the Renal Tubule by Regulating E-cadherin through Targeting KDM6A in Diabetic Nephropathy

Diabetic nephropathy (DN) is the leading cause of end-stage renal disease. The association between epithelial-mesenchymal transition (EMT) and fibrosis is quite ascertained, but its link to eventual tubule dysfunction is missing. Here, we show that human microRNA- (hsa-miR-) 199b-3p protects renal t...

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Détails bibliographiques
Publié dans:Oxid Med Cell Longev
Auteurs principaux: Bai, Shoujun, Xiong, Xiaoyan, Tang, Bo, Ji, Tingting, Li, Xiaoying, Qu, Xiaolei, Li, Weiliang
Format: Artigo
Langue:Inglês
Publié: Hindawi 2021
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8257373/
https://ncbi.nlm.nih.gov/pubmed/34257820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2021/8814163
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