Ankyrin-R regulates fast-spiking interneuron excitability through perineuronal nets and Kv3.1b K(+) channels

Neuronal ankyrins cluster and link membrane proteins to the actin and spectrin-based cytoskeleton. Among the three vertebrate ankyrins, little is known about neuronal Ankyrin-R (AnkR). We report AnkR is highly enriched in Pv(+) fast-spiking interneurons in mouse and human. We identify AnkR-associate...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Stevens, Sharon R, Longley, Colleen M, Ogawa, Yuki, Teliska, Lindsay H, Arumanayagam, Anithachristy S, Nair, Supna, Oses-Prieto, Juan A, Burlingame, Alma L, Cykowski, Matthew D, Xue, Mingshan, Rasband, Matthew N
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2021
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8257253/
https://ncbi.nlm.nih.gov/pubmed/34180393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.66491
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