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Potential Prospect of CDK4/6 Inhibitors in Triple-Negative Breast Cancer

Triple-negative breast cancer (TNBC) is an aggressive, difficult-to-treat subtype of cancer with a poor prognosis; there is an urgent need for effective, targeted molecular therapies. The cyclin D/cyclin-dependent kinase (CDK)4/6–retinoblastoma protein (Rb) pathway plays a critical role in regulatin...

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Detalles Bibliográficos
Publicado en:Cancer Manag Res
Main Authors: Hu, Ye, Gao, Jiyue, Wang, Meiling, Li, Man
Formato: Artigo
Idioma:Inglês
Publicado: Dove 2021
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8257068/
https://ncbi.nlm.nih.gov/pubmed/34234565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CMAR.S310649
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