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A reaction pathway to compound 0 intermediates in oxy-myoglobin through interactions with hydrogen sulfide and His64

Myoglobin (Mb) binds oxygen with high affinity as a low spin singlet complex and thus functions as an oxygen storage protein. Yet, hybrid Density Functional Theory/Molecular Mechanical (DFT/MM) calculations of oxy-Mb models predict that the O(2) bond is much less resistant to breaking in the presenc...

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Detalhes bibliográficos
Publicado no:J Mol Graph Model
Main Authors: Rodriguez-Mackenzie, Angel D., Arbelo-Lopez, Hector D., Wymore, Troy, Lopez-Garriga, Juan
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8256827/
https://ncbi.nlm.nih.gov/pubmed/31670138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmgm.2019.107465
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