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Downregulation of Tim-1 inhibits the proliferation, migration and invasion of glioblastoma cells via the miR-133a/TGFBR1 axis and the restriction of Wnt/β-catenin pathway

BACKGROUND: Glioblastoma remains one of the most lethal brain cancers. T-cell immunoglobulin and mucin domain 1 (Tim-1) is associated with various immune diseases. The molecular mechanism of Tim-1 in regulating glioblastoma cell proliferation, invasion, and migration is still unknown. Moreover, it h...

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Detalhes bibliográficos
Publicado no:Cancer Cell Int
Main Authors: Wei, Li, Peng, Ya, Shao, Naiyuan, Zhou, Peng
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8256541/
https://ncbi.nlm.nih.gov/pubmed/34225723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12935-021-02036-1
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