Sensing of mycobacterial arabinogalactan by galectin‐9 exacerbates mycobacterial infection

Mycobacterial arabinogalactan (AG) is an essential cell wall component of mycobacteria and a frequent structural and bio‐synthetical target for anti‐tuberculosis (TB) drug development. Here, we report that mycobacterial AG is recognized by galectin‐9 and exacerbates mycobacterial infection. Administ...

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Gepubliceerd in:EMBO Rep
Hoofdauteurs: Wu, Xiangyang, Wu, Yong, Zheng, Ruijuan, Tang, Fen, Qin, Lianhua, Lai, Detian, Zhang, Lu, Chen, Lingming, Yan, Bo, Yang, Hua, Wang, Yang, Li, Feifei, Zhang, Jinyu, Wang, Fei, Wang, Lin, Cao, Yajuan, Ma, Mingtong, Liu, Zhonghua, Chen, Jianxia, Huang, Xiaochen, Wang, Jie, Jin, Ruiliang, Wang, Peng, Sun, Qin, Sha, Wei, Lyu, Liangdong, Moura‐Alves, Pedro, Dorhoi, Anca, Pei, Gang, Zhang, Peng, Chen, Jiayu, Gao, Shaorong, Randow, Felix, Zeng, Gucheng, Chen, Chang, Ye, Xin‐Shan, Kaufmann, Stefan H E, Liu, Haipeng, Ge, Baoxue
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: John Wiley and Sons Inc. 2021
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8256295/
https://ncbi.nlm.nih.gov/pubmed/33987949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.202051678
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