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A re-examination of the SPYRAL HTN-OFF MED Pivotal trial with respect to the underlying model assumptions

BACKGROUND: The SPYRAL HTN-OFF MED Pivotal trial demonstrated that RDN was efficacious compared to a sham control. The underlying model was an extension of the analysis of covariance (ANCOVA) model, adjusted for baseline blood pressure (BP), and allowed borrowing of information from the previously r...

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Detalhes bibliográficos
Publicado no:Contemp Clin Trials Commun
Main Authors: Böhm, Michael, Fahy, Martin, Hickey, Graeme L., Pocock, Stuart, Brar, Sandeep, DeBruin, Vanessa, Weber, Michael A., Mahfoud, Felix, Kandzari, David E.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8256182/
https://ncbi.nlm.nih.gov/pubmed/34258470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.conctc.2021.100818
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