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Elucidation of the molecular interactions that enable stable assembly and structural diversity in multicomponent immune receptors

Multicomponent immune receptors are essential complexes in which distinct ligand-recognition and signaling subunits are held together by interactions between acidic and basic residues of their transmembrane helices. A 2:1 acidic-to-basic motif in the transmembrane domains of the subunits is necessar...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Fong, Lam-Kiu, Chalkley, Matthew J., Tan, Sophia K., Grabe, Michael, DeGrado, William F.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8256006/
https://ncbi.nlm.nih.gov/pubmed/34155106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2026318118
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