OMRT-3. Longitudinal analysis of diffuse glioma reveals cell state dynamics at recurrence associated with changes in genetics and the microenvironment

Diffuse glioma is an aggressive brain cancer that is characterized by a poor prognosis and a universal resistance to therapy. The evolutionary processes behind this resistance remain unclear. Previous studies by the Glioma Longitudinal Analysis (GLASS) Consortium have indicated that therapy-induced...

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Veröffentlicht in:Neurooncol Adv
Hauptverfasser: Varn, Frederick, Johnson, Kevin, Barthel, Floris, Kim, Hoon, Wade, Taylor, Malta, Tathiane, Sabedot, Thais, Lodha, Disha, Ajaib, Shoaib, Ahmed, Nazia, Garofano, Luciano, D’Angelo, Fulvio, Stead, Lucy, Poisson, Laila, Noushmehr, Houtan, Iavarone, Antonio, Verhaak, Roel
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2021
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8255447/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/noajnl/vdab070.029
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