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OTME-18. Targeted CRISPR/Cas9 gene-editing regulates the brain tumor environment

Glioblastoma multiform (GBM) is the most common malignant brain tumor. Recent immunotherapy has demonstrated potential to treat GBM. However, the immune suppressive tumor environment in the brain represents a significant barrier for the treatment of GBM. Overexpression of programmed death ligand-1 (...

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Detalhes bibliográficos
Publicado no:Neurooncol Adv
Main Authors: Perez, Joshua, Fierro, Javier, Aguilar, Rocio, Dou, Huanyu
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8255424/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/noajnl/vdab070.069
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