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Exposure of the cytoplasm to low-dose X-rays modifies ataxia telangiectasia mutated-mediated DNA damage responses

We recently showed that when a low X-ray dose is used, cell death is enhanced in nucleus-irradiated compared with whole-cell-irradiated cells; however, the role of the cytoplasm remains unclear. Here, we show changes in the DNA damage responses with or without X-ray microbeam irradiation of the cyto...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Maeda, Munetoshi, Tomita, Masanori, Maeda, Mika, Matsumoto, Hideki, Usami, Noriko, Kume, Kyo, Kobayashi, Katsumi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8255317/
https://ncbi.nlm.nih.gov/pubmed/34219128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-92213-z
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