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Novel piperazine based compounds as potential inhibitors for SARS-CoV-2 Protease Enzyme: Synthesis and molecular docking study

Structurally diverse piperazine-based compounds hybrid with thiadiazole, isatin or with sulfur/nitrogen, functionalities were synthesized. The structures of the new compounds were established based on their spectral data and elemental analysis. The physicochemical, bioactivity scores and pharmacokin...

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Detalhes bibliográficos
Publicado no:J Mol Struct
Main Authors: Omar, Alaa Z., Mosa, Tawfik M., El-sadany, Samer K., Hamed, Ezzat A., El-atawy, Mohamed
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier B.V. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8255031/
https://ncbi.nlm.nih.gov/pubmed/34248201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molstruc.2021.131020
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