Homer1 promotes dendritic spine growth through ankyrin-G and its loss reshapes the synaptic proteome

Homer1 is a synaptic scaffold protein that regulates glutamatergic synapses and spine morphogenesis. HOMER1 knockout (KO) mice show behavioral abnormalities related to psychiatric disorders, and HOMER1 has been associated with psychiatric disorders such as addiction, autism disorder (ASD), schizophr...

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Publicat a:Mol Psychiatry
Autors principals: Yoon, Sehyoun, Piguel, Nicolas H., Khalatyan, Natalia, Dionisio, Leonardo E., Savas, Jeffrey N., Penzes, Peter
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2021
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8254828/
https://ncbi.nlm.nih.gov/pubmed/33398084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41380-020-00991-1
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