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Genome-wide CRISPRi/a screens in human neurons link lysosomal failure to ferroptosis
Single-cell transcriptomics provide a systematic map of gene expression in different human cell types. The next challenge is to systematically understand cell-type specific gene function. The integration of CRISPR-based functional genomics and stem cell technology enables the scalable interrogation...
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| Izdano u: | Nat Neurosci |
|---|---|
| Glavni autori: | , , , , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2021
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8254803/ https://ncbi.nlm.nih.gov/pubmed/34031600 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41593-021-00862-0 |
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