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Integrin α4β1 is required for IL-1α- and Nrf2-dependent, Cox-2 induction in fibroblasts, supporting a mechanism that suppresses α-SMA expression.

Growth and repair processes, both normal and pathological, require reciprocal interactions between cells and their microenvironment. Integrins are bidirectional, cell surface receptors that transduce mechanical and chemical signals to and from the extracellular matrix. We recently reported that kera...

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Detalhes bibliográficos
Publicado no:Wound Repair Regen
Main Authors: Zheng, Rui, Varney, Scott, Wu, Lei, DiPersio, C Michael, Van De Water, Livingston
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8254763/
https://ncbi.nlm.nih.gov/pubmed/34046979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/wrr.12938
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