Amniotic Fluid IL-6 and IL-8 Are Superior Predictors of Fetal Lung Injury Compared to Maternal or Fetal Plasma Cytokines or Placental Histopathology in a Nonhuman Primate Model

BACKGROUND: Intra-amniotic infection or inflammation (IAI) is common in early preterm birth and associated with significant neonatal lung morbidity due to fetal exposure to pro-inflammatory cytokines and infectious organisms. Amniotic fluid interleukin-8 (IL-8), a pro-inflammatory cytokine, was prev...

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Bibliographic Details
Published in:Am J Obstet Gynecol
Main Authors: MCCARTNEY, Stephen A., KAPUR, Raj, LIGGITT, H. Denny, BALDESSARI, Audrey, COLEMAN, Michelle, ORVIS, Austyn, OGLE, Jason, KATZ, Ronit, RAJAGOPAL, Lakshmi, ADAMS WALDORF, Kristina M.
Format: Artigo
Language:Inglês
Published: 2021
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8254735/
https://ncbi.nlm.nih.gov/pubmed/33412130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajog.2020.12.1214
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