Volatile Anesthetic Sevoflurane Precursor 1,1,1,3,3,3-Hexafluoro-2-Propanol (HFIP) Exerts an Anti-Prion Activity in Prion-Infected Culture Cells

Prion disease is a neurodegenerative disorder with progressive neurologic symptoms and accelerated cognitive decline. The causative protein of prion disease is the prion protein (PrP), and structural transition of PrP from the normal helix rich form (PrP(C)) to the abnormal β-sheet rich form (PrP(Sc...

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Bibliographic Details
Published in:Neurochem Res
Main Authors: Shimizu, Takuto, Nogami, Emiko, Ito, Yuka, Morikawa, Kazuo, Nagane, Masaki, Yamashita, Tadashi, Ogawa, Tsuyoshi, Kametani, Fuyuki, Yagi, Hisashi, Hachiya, Naomi
Format: Artigo
Language:Inglês
Published: Springer US 2021
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Original Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8254714/
https://ncbi.nlm.nih.gov/pubmed/34043140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11064-021-03344-8
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