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Y-27632, a ROCK inhibitor, improved laser-induced shock wave (LISW)-induced cochlear synaptopathy in mice

Recently, a pathological condition called cochlear synaptopathy has been clarified, and as a disorder of the auditory nerve synapses that occurs prior to failure of hair cells, it has been recognized as a major cause of sensorineural hearing loss. However, cochlear synaptopathy is untreatable. Inhib...

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Détails bibliographiques
Publié dans:Mol Brain
Auteurs principaux: Koizumi, Yutaka, Mizutari, Kunio, Kawauchi, Satoko, Sato, Shunichi, Shiotani, Akihiro, Kakehata, Seiji
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2021
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8254252/
https://ncbi.nlm.nih.gov/pubmed/34217338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13041-021-00819-1
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