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Identification and quantification of glucose degradation products in heat-sterilized glucose solutions for parenteral use by thin-layer chromatography

During heat sterilization of glucose solutions, a variety of glucose degradation products (GDPs) may be formed. GDPs can cause cytotoxic effects after parenteral administration of these solutions. The aim of the current study therefore was to develop a simple and quick high-performance thin-layer ch...

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Publicat a:PLoS One
Autors principals: Leitzen, Sarah, Vogel, Matthias, Engels, Anette, Zapf, Thomas, Brandl, Martin
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2021
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8253424/
https://ncbi.nlm.nih.gov/pubmed/34214128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0253811
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