Hypertonic Saline is Superior to Mannitol for the Combined Effect on Intracranial Pressure and Cerebral Perfusion Pressure Burdens in Patients With Severe Traumatic Brain Injury

BACKGROUND: Hypertonic saline (HTS) and mannitol are effective in reducing intracranial pressure (ICP) after severe traumatic brain injury (TBI). However, their simultaneous effect on the cerebral perfusion pressure (CPP) and ICP has not been studied rigorously. OBJECTIVE: To determine the differenc...

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Detalhes bibliográficos
Publicado no:Neurosurgery
Main Authors: Mangat, Halinder S, Wu, Xian, Gerber, Linda M, Schwarz, Justin T, Fakhar, Malik, Murthy, Santosh B, Stieg, Philip E, Ghajar, Jamshid, Härtl, Roger
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Research—Human—Clinical Studies
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8253301/
https://ncbi.nlm.nih.gov/pubmed/30877299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuros/nyz046
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