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Heat shock protein 47 confers chemoresistance on pancreatic cancer cells by interacting with calreticulin and IRE1α

Pancreatic ductal adenocarcinoma (PDAC) is one of the most chemoresistant cancers. An understanding of the molecular mechanism by which PDAC cells have a high chemoresistant potential is important for improvement of the poor prognosis of patients with PDAC. Here we show for the first time that disru...

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Détails bibliographiques
Publié dans:Cancer Sci
Auteurs principaux: Yoneda, Akihiro, Minomi, Kenjiro, Tamura, Yasuaki
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2021
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8253297/
https://ncbi.nlm.nih.gov/pubmed/34109710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.14976
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