RAG enhances BCR‐ABL1‐positive leukemic cell growth through its endonuclease activity in vitro and in vivo

BCR‐ABL1 gene fusion associated with additional DNA lesions involves the pathogenesis of chronic myelogenous leukemia (CML) from a chronic phase (CP) to a blast crisis of B lymphoid (CML‐LBC) lineage and BCR‐ABL1 (+) acute lymphoblastic leukemia (BCR‐ABL1 (+) ALL). The recombination‐activating gene...

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Publicado en:Cancer Sci
Autores principales: Yuan, Meng, Wang, Yang, Qin, Mengting, Zhao, Xiaohui, Chen, Xiaodong, Li, Dandan, Miao, Yinsha, Otieno Odhiambo, Wood, Liu, Huasheng, Ma, Yunfeng, Ji, Yanhong
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2021
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Original Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8253288/
https://ncbi.nlm.nih.gov/pubmed/33949040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.14939
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