Characterisation of Bacteriophage-Encoded Depolymerases Selective for Key Klebsiella pneumoniae Capsular Exopolysaccharides

Capsular polysaccharides enable clinically important clones of Klebsiella pneumoniae to cause severe systemic infections in susceptible hosts. Phage-encoded capsule depolymerases have the potential to provide an alternative treatment paradigm in patients when multiple drug resistance has eroded the...

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Detalles Bibliográficos
Publicado en:Front Cell Infect Microbiol
Main Authors: Blundell-Hunter, George, Enright, Mark C., Negus, David, Dorman, Matthew J., Beecham, Gemma E., Pickard, Derek J., Wintachai, Phitchayapak, Voravuthikunchai, Supayang P., Thomson, Nicholas R., Taylor, Peter W.
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2021
Assuntos:
Cellular and Infection Microbiology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8253255/
https://ncbi.nlm.nih.gov/pubmed/34222050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcimb.2021.686090
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