High drug payload curcumin nanosuspensions stabilized by mPEG-DSPE and SPC: in vitro and in vivo evaluation

Context: Curcumin (CUR) is a promising drug candidate based on its broad bioactivities and good antitumor effect, but the application of CUR is potentially restricted because of its poor solubility and bioavailability. Objective: This study aims at developing a simple and effective drug delivery sys...

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Veröffentlicht in:Drug Deliv
Hauptverfasser: Hong, Jingyi, Liu, Yingying, Xiao, Yao, Yang, Xiaofeng, Su, Wenjing, Zhang, Mingzhu, Liao, Yonghong, Kuang, Haixue, Wang, Xiangtao
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 2017
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8253124/
https://ncbi.nlm.nih.gov/pubmed/28155567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10717544.2016.1233589
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