Clinical efficacy of T-cell therapy after short-term BRAF-inhibitor priming in patients with checkpoint inhibitor-resistant metastatic melanoma

PURPOSE: Despite impressive response rates following adoptive transfer of autologous tumor-infiltrating lymphocytes (TILs) in patients with metastatic melanoma, improvement is needed to increase the efficacy and broaden the applicability of this treatment. We evaluated the use of vemurafenib, a smal...

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Udgivet i:J Immunother Cancer
Main Authors: Borch, Troels Holz, Harbst, Katja, Rana, Aynal Haque, Andersen, Rikke, Martinenaite, Evelina, Kongsted, Per, Pedersen, Magnus, Nielsen, Morten, Kjeldsen, Julie Westerlin, Kverneland, Anders Handrup, Lauss, Martin, Hölmich, Lisbet Rosenkrantz, Hendel, Helle, Met, Özcan, Jönsson, Göran, Donia, Marco, Marie Svane, Inge
Format: Artigo
Sprog:Inglês
Udgivet: BMJ Publishing Group 2021
Fag:
Immune Cell Therapies and Immune Cell Engineering
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8252872/
https://ncbi.nlm.nih.gov/pubmed/34210820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jitc-2021-002703
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