Genomewide Association Studies of LRRK2 Modifiers of Parkinson's Disease

OBJECTIVE: The aim of this study was to search for genes/variants that modify the effect of LRRK2 mutations in terms of penetrance and age‐at‐onset of Parkinson's disease. METHODS: We performed the first genomewide association study of penetrance and age‐at‐onset of Parkinson's disease in...

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Publicado en:Ann Neurol
Main Authors: Lai, Dongbing, Alipanahi, Babak, Fontanillas, Pierre, Schwantes‐An, Tae‐Hwi, Aasly, Jan, Alcalay, Roy N., Beecham, Gary W., Berg, Daniela, Bressman, Susan, Brice, Alexis, Brockman, Kathrin, Clark, Lorraine, Cookson, Mark, Das, Sayantan, Van Deerlin, Vivianna, Follett, Jordan, Farrer, Matthew J., Trinh, Joanne, Gasser, Thomas, Goldwurm, Stefano, Gustavsson, Emil, Klein, Christine, Lang, Anthony E., Langston, J. William, Latourelle, Jeanne, Lynch, Timothy, Marder, Karen, Marras, Connie, Martin, Eden R., McLean, Cory Y., Mejia‐Santana, Helen, Molho, Eric, Myers, Richard H., Nuytemans, Karen, Ozelius, Laurie, Payami, Haydeh, Raymond, Deborah, Rogaeva, Ekaterina, Rogers, Michael P., Ross, Owen A., Samii, Ali, Saunders‐Pullman, Rachel, Schüle, Birgitt, Schulte, Claudia, Scott, William K., Tanner, Caroline, Tolosa, Eduardo, Tomkins, James E., Vilas, Dolores, Trojanowski, John Q., Uitti, Ryan, Vance, Jeffery M., Visanji, Naomi P., Wszolek, Zbigniew K., Zabetian, Cyrus P., Mirelman, Anat, Giladi, Nir, Orr Urtreger, Avi, Cannon, Paul, Fiske, Brian, Foroud, Tatiana
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley & Sons, Inc. 2021
Assuntos:
Research Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8252519/
https://ncbi.nlm.nih.gov/pubmed/33938021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.26094
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