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Pathway testing for longitudinal metabolomics
We propose a top‐down approach for pathway analysis of longitudinal metabolite data. We apply a score test based on a shared latent process mixed model which can identify pathways with differentially progressing metabolites. The strength of our approach is that it can handle unbalanced designs, deal...
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| Pubblicato in: | Stat Med |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
John Wiley and Sons Inc.
2021
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8252476/ https://ncbi.nlm.nih.gov/pubmed/33768548 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sim.8957 |
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