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The Folding Landscapes of Human Telomeric RNA and DNA G‐Quadruplexes are Markedly Different
We investigated the folding kinetics of G‐quadruplex (G4) structures by comparing the K(+)‐induced folding of an RNA G4 derived from the human telomeric repeat‐containing RNA (TERRA25) with a sequence homologous DNA G4 (wtTel25) using CD spectroscopy and real‐time NMR spectroscopy. While DNA G4 fold...
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| Veröffentlicht in: | Angew Chem Int Ed Engl |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
John Wiley and Sons Inc.
2021
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8252441/ https://ncbi.nlm.nih.gov/pubmed/33539622 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.202100280 |
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