Enzyme‐Primed Native Chemical Ligation Produces Autoinducing Cyclopeptides in Clostridia

Clostridia coordinate many important processes such as toxin production, infection, and survival by density‐dependent communication (quorum sensing) using autoinducing peptides (AIPs). Although clostridial AIPs have been proposed to be (thio)lactone‐containing peptides, their true structures remain...

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Veröffentlicht in:Angew Chem Int Ed Engl
Hauptverfasser: Molloy, Evelyn M., Dell, Maria, Hänsch, Veit G., Dunbar, Kyle L., Feldmann, Romy, Oberheide, Ansgar, Seyfarth, Lydia, Kumpfmüller, Jana, Horch, Therese, Arndt, Hans‐Dieter, Hertweck, Christian
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2021
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Research Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8251862/
https://ncbi.nlm.nih.gov/pubmed/33625794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.202016378
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