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Enzyme‐Primed Native Chemical Ligation Produces Autoinducing Cyclopeptides in Clostridia

Clostridia coordinate many important processes such as toxin production, infection, and survival by density‐dependent communication (quorum sensing) using autoinducing peptides (AIPs). Although clostridial AIPs have been proposed to be (thio)lactone‐containing peptides, their true structures remain...

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Vydáno v:Angew Chem Int Ed Engl
Hlavní autoři: Molloy, Evelyn M., Dell, Maria, Hänsch, Veit G., Dunbar, Kyle L., Feldmann, Romy, Oberheide, Ansgar, Seyfarth, Lydia, Kumpfmüller, Jana, Horch, Therese, Arndt, Hans‐Dieter, Hertweck, Christian
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8251862/
https://ncbi.nlm.nih.gov/pubmed/33625794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.202016378
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