Is cerebrospinal fluid amyloid‐β42 a promising biomarker of response to nusinersen in adult spinal muscular atrophy patients?

INTRODUCTION: Nusinersen was approved as the first treatment for all types of spinal muscular atrophy (SMA), including adults with SMA types 2 and 3. Robust biomarkers of treatment response in SMA adults are lacking. Our aim was to examine cerebrospinal fluid (CSF) amyloid‐β40 (Aβ40) and amyloid‐β42...

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Dettagli Bibliografici
Pubblicato in:Muscle Nerve
Autori principali: Introna, Alessandro, Milella, Giammarco, D'Errico, Eustachio, Fraddosio, Angela, Scaglione, Gaspare, Ucci, Maria, Ruggieri, Maddalena, Simone, Isabella Laura
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley & Sons, Inc. 2021
Soggetti:
Clinical Research Short Reports
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8251706/
https://ncbi.nlm.nih.gov/pubmed/33660868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mus.27212
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