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Intracellular amyloid hypothesis for ultra‐early phase pathology of Alzheimer's disease

Using a new marker of necrosis, pSer46‐MARCKS, which was identified by comprehensive phosphoproteome analysis as a phosphoprotein changed before appearance of extracellular amyloid aggregation, we discovered that neuronal necrosis occurs much earlier in Alzheimer's disease pathology than previo...

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Detalhes bibliográficos
Publicado no:Neuropathology
Autor principal: Okazawa, Hitoshi
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons Australia, Ltd 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8251586/
https://ncbi.nlm.nih.gov/pubmed/33876503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/neup.12738
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