An Endoplasmic Reticulum Specific Pro‐amplifier of Reactive Oxygen Species in Cancer Cells

The folding and export of proteins and hydrolysis of unfolded proteins are disbalanced in the endoplasmic reticulum (ER) of cancer cells, leading to so‐called ER stress. Agents further augmenting this effect are used as anticancer drugs including clinically approved proteasome inhibitors bortezomib...

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Publicat a:Angew Chem Int Ed Engl
Autors principals: Xu, Hong‐Gui, Schikora, Margot, Sisa, Miroslav, Daum, Steffen, Klemt, Insa, Janko, Christina, Alexiou, Christoph, Bila, Galyna, Bilyy, Rostyslav, Gong, Wenjie, Schmitt, Michael, Sellner, Leopold, Mokhir, Andriy
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2021
Matèries:
Communications
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8251580/
https://ncbi.nlm.nih.gov/pubmed/33656236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.202100054
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