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Silencing of SARS‐CoV‐2 with modified siRNA‐peptide dendrimer formulation

BACKGROUND: First vaccines for prevention of Coronavirus disease 2019 (COVID‐19) are becoming available but there is a huge and unmet need for specific forms of treatment. In this study we aimed to evaluate the anti‐SARS‐CoV‐2 effect of siRNA both in vitro and in vivo. METHODS: To identify the most...

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Detalhes bibliográficos
Publicado no:Allergy
Main Authors: Khaitov, Musa, Nikonova, Alexandra, Shilovskiy, Igor, Kozhikhova, Ksenia, Kofiadi, Ilya, Vishnyakova, Lyudmila, Nikolskii, Alexander, Gattinger, Pia, Kovchina, Valeria, Barvinskaia, Ekaterina, Yumashev, Kirill, Smirnov, Valeriy, Maerle, Artem, Kozlov, Ivan, Shatilov, Artem, Timofeeva, Anastasiia, Andreev, Sergey, Koloskova, Olesya, Kuznetsova, Nadezhda, Vasina, Daria, Nikiforova, Maria, Rybalkin, Sergei, Sergeev, Ilya, Trofimov, Dmitriy, Martynov, Alexander, Berzin, Igor, Gushchin, Vladimir, Kovalchuk, Aleksey, Borisevich, Sergei, Valenta, Rudolf, Khaitov, Rakhim, Skvortsova, Veronica
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8251148/
https://ncbi.nlm.nih.gov/pubmed/33837568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/all.14850
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