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Exocrine pancreas proteases regulate β-cell proliferation in zebrafish ciliopathy models and in murine systems

Pancreatic β-cells are a critical cell type in the pathology of diabetes. Models of genetic syndromes featuring diabetes can provide novel mechanistic insights into regulation of β-cells in the context of disease. We previously examined β-cell mass in models of two ciliopathies, Alström Syndrome (AS...

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Detalhes bibliográficos
Publicado no:Biol Open
Main Authors: Hostelley, Timothy L., Nesmith, Jessica E., Larkin, Emily, Jones, Amanda, Boyes, Daniel, Leitch, Carmen C., Fontaine, Magali, Zaghloul, Norann A.
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8249909/
https://ncbi.nlm.nih.gov/pubmed/34125181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.046839
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