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APP, PSEN1, and PSEN2 Variants in Alzheimer’s Disease: Systematic Re-evaluation According to ACMG Guidelines

The strategies of classifying APP, PSEN1, and PSEN2 variants varied substantially in the previous studies. We aimed to re-evaluate these variants systematically according to the American college of medical genetics and genomics and the association for molecular pathology (ACMG-AMP) guidelines. In ou...

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Bibliografiske detaljer
Udgivet i:Front Aging Neurosci
Main Authors: Xiao, Xuewen, Liu, Hui, Liu, Xixi, Zhang, Weiwei, Zhang, Sizhe, Jiao, Bin
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8249733/
https://ncbi.nlm.nih.gov/pubmed/34220489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2021.695808
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