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Effects of Ribosomal Protein S10 Flexible Loop Mutations on Tetracycline and Tigecycline Susceptibility of Escherichia coli

Tigecycline is a tetracycline derivative that is being used as an antibiotic of last resort. Both tigecycline and tetracycline bind to the small (30S) ribosomal subunit and inhibit translation. Target mutations leading to resistance to these antibiotics have been identified both in the 16S ribosomal...

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Vydáno v:Front Microbiol
Hlavní autoři: Izghirean, Norbert, Waidacher, Claudia, Kittinger, Clemens, Chyba, Miriam, Koraimann, Günther, Pertschy, Brigitte, Zarfel, Gernot
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2021
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8249722/
https://ncbi.nlm.nih.gov/pubmed/34220749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2021.663835
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