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Cyclooxygenase inhibition attenuates brain angiogenesis and independently decreases mouse survival under hypoxia

Although cyclooxygenase (COX) role in cancer angiogenesis has been studied, little is known about its role in brain angioplasticity. In the present study, we chronically infused mice with ketorolac, a non‐specific COX inhibitor that does not cross the blood–brain barrier (BBB), under normoxia or 50%...

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書目詳細資料
發表在:J Neurochem
Main Authors: Seeger, Drew R., Golovko, Svetlana A., Grove, Bryon D., Golovko, Mikhail Y.
格式: Artigo
語言:Inglês
出版: John Wiley and Sons Inc. 2021
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC8249483/
https://ncbi.nlm.nih.gov/pubmed/33389746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.15291
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