A Model-Informed Method for the Purpose of Precision Dosing of Isoniazid in Pulmonary Tuberculosis

BACKGROUND AND OBJECTIVE: This study aimed to develop and evaluate a population pharmacokinetic model and limited sampling strategy for isoniazid to be used in model-based therapeutic drug monitoring. METHODS: A population pharmacokinetic model was developed based on isoniazid and acetyl-isoniazid p...

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Publicat a:Clin Pharmacokinet
Autors principals: van Beek, Stijn W., ter Heine, Rob, Alffenaar, Jan-Willem C., Magis-Escurra, Cecile, Aarnoutse, Rob E., Svensson, Elin M.
Format: Artigo
Idioma:Inglês
Publicat: Springer International Publishing 2021
Matèries:
Original Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8249295/
https://ncbi.nlm.nih.gov/pubmed/33615419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40262-020-00971-2
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