Melatonin Attenuates Intervertebral Disk Degeneration via Maintaining Cartilaginous Endplate Integrity in Rats

OBJECTIVE: The aim of this study is to verify whether melatonin (Mel) could mitigate intervertebral disk degeneration (IVDD) in rats and to investigate the potential mechanism of it. METHOD: A rat acupuncture model of IVDD was established with intraperitoneal injection of Mel. The effect of Mel on I...

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Publicat a:Front Physiol
Autors principals: Wu, Xiexing, Liu, Yijie, Du, Jiacheng, Li, Xiaoping, Lin, Jiayi, Ni, Li, Zhu, Pengfei, Zhou, Hong, Kong, Fanchen, Yang, Huilin, Geng, Dechun, Mao, Haiqing
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2021
Matèries:
Physiology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8248798/
https://ncbi.nlm.nih.gov/pubmed/34220535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2021.672572
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